Exercise Supplementation Quickie Optimal Protein Blend for Protein Synthesis Gout Drug for Muscle Protection Plus 3 Suggestions for Optimal Protein Blends

Dont obsess about "optimal" supplement regimen, start training, eating, sleeping and exercise the patience it takes to reverse years of sedentary pizza eating.

I thought it would be nice to take a closer look at some of the news I would otherwise "waste" in form of a three-liner in the SuppVersity Facebook News and decided that it was about time for yet another "news quickie" on exercise supplementation and exercise & supplementation ;-)

For todays installment of these "Short News", Ive selected a study that discusses the impressive effects of a "gout drug" on exercise induced muscle damage and a study that takes another look at the ever-so-popular issue of "optimal" protein supplementation - an issue some of you are investing so much energy in that it is no wonder that theyre not making the gains they would want to.

You can learn more about protein intake at the SuppVersity

Are You Protein Wheysting?

Cod protein for recovery

Protein requ. of athletes

High EAA protein for fat loss

Fast vs. slow protein

Too much ado about protein?

• Interesting observation: Xanthine oxidase inhibitor Allopurinol, which is usually used to treat conditions that are cause by increased uric acid levels (e.g. gout), dampens exercise induced muscle damage in trained individuals.
  
  The results of a recent study from the University of Valencia clearly demonstrate that the use of 300 mg of allopurinol 4h before a soccer match, lead to significant reductions in all measured markers of muscle damage in those six out of twelve professional soccer players who had been randomized to the active arm of the study (Sanshis Gomar. 2014).

  

  Figure 1: Changes in markers of muscle, heart and liver damage, as well as MDA levels, amarker of lipid oxidation due to soccer match with our without xanthine oxidase inhibitor (Sanshis Gomar. 2014)

  Now, unfortunately, a reduction in muscle damage that is facilitated by the inhibition of an enzyme that generates reactive oxygen species is - as you should by now have learnt from the dozens of posts on hormesis and the beneficial effects of exercise induced increases in reactive oxygen specie, not exactly desirable.
  
  The authors conclusion that their observation was a great thing and could be used by athletes all around the world is thus probably only valid with respect to in professional soccer players and other elite athletes who are trying to avoid overuse injuries... and even for their health blunting the ROS response to exercise permanently probably isnt going to be exactly conducive to their health.
• Further evidence for the superiority of protein blends (vs. single sources as whey) for muscle building
  
  Scientists from the University of Texas Medical Branch, the Texas A&M University, the Arizona State University and the University of Utah found that a blend of soy and dairy protein slightly prolonged net amino acid balance across the leg as compared to whey protein alone, when it was ingested right after a workout.

Remember? Only recently youve learned here at the SuppVersity that Whey + Casein outperform Whey + BCAA + Glutamine and you bet that this combo will also outshadow the combination of whey, a fast digesting protein and soy, with an only minimally more sustained digestion pofile (for suggestions see bullet-points below).

• In the soon-to-be-published paper, to which I do unfortunately not have access, the scientists emphasize that it is not the fractional protein synthesis rate or the mRNA expression of selected amino acid transporters (LAT1/SLC7A5, CD98/SLC3A2 SNAT2/SLC38A2, PAT1/SLC36A1, CAT1/SLC7A1) which made the difference, but rather the fact hat "the ingestion of the protein blend resulted in a prolonged and positive net phenylalanine balance during post-exercise recovery as compared to whey protein" (Reidy. 2014).
  
  Now, eventually this is no news. I wrote about a similar phenomenon with whey protein only recently (learn more) and some of the researchers who were part of the study at hand have actually presented very similar results (albeit from a rodent study) in the August edition of Clinical Nutrition last year.
  

  

  Figure 2: Fractional protein synthesis 0-270min after the ingestion of pure whey or soy isolate of blends containing soy, whey and caseinate in the given ratios (Butteiger. 2013)

  In this study Butteiger et al. observed that a mixture of 1:1:2 of soy protein, whey protein and caseinate (="broken" micelar casein which has a significantly faster digestion rate than the original) produced the maximal increase in protein synthesis (dotted line in Figure 1), but with "fake casein" and soy, I am 100% sure that you can do better than that with whey hydrolysate, whey concentrate and micellar casein (1:1:1 would mean an identical ratio of the three). As far as the ratios goes, I would suggest the following combinations for specific purposes:
  
  • 5:5:1 - immediately post workout, if you have a meal within the next 1h
  • 1:1:1 - immediately post workout, if you have a meal within the next 2h
  • 1:3:5 - as a snack, of if you dont have a meal within 4h of the workout
  Please keep in mind, though that I have no scientific evidence to confirm that this would be "optimal" - its just what I would say appears logical based on the current evidence we have. Instead of whey hydrolysate you can also replace this and the whey concentrate by an isolate. So that you would end up at whey isolate : micellar casein ratios of 10:1, 2:1 and 4:5 - got that?

Bottom line: Eventually, there is just one practical conclusion to be drawn from todays news potpourri: There is no need to limit your net protein synthesis with "pure" whey proteins, because this is what most studies use and many of the bros recommend.

 +43% Muscle Glycogen With Whey vs. Amino Acid Mix | learn more

As far as the use of xanthine oxidase inhibitors are concerned, I have my doubts whether that is not going to produce more problems than solve. And as far as the "optimal" ratio of fast- to slow-digesting proteins for maximal protein anabolism is concerned, I can only tell you that it would require 100 studies to get a decently reliable idea of what the "real" optimum for a certain population and training style was.... but dont grudge. In the end those few %-ages of FSR certainly wont be the reason you are not making the gains you are aspiring - so keep looking for excuses and start removing the true obstacles that are standing between yourself and the physique of your dreams.

References:

• Butteiger, D. N., et al. "A soy, whey and caseinate blend extends postprandial skeletal muscle protein synthesis in rats." Clinical Nutrition 32.4 (2013): 585-591.
• Reidy, et al. "Soy-Dairy Protein Blend and Whey Protein Ingestion After Resistance Exercise Increases Amino Acid Transport and Transporter Expression in Human Skeletal Muscle." Journal of Applied Physiology April 3, 2014 jap.01093.2013 
• Sanchis‐Gomar, F., et al. "Allopurinol prevents cardiac and skeletal muscle damage in professional soccer players." Scandinavian Journal of Medicine & Science in Sports (2014).

How You Can Stay Healthy With These 13 Reasons to Exercise

Patti Goewey shares her recent article on these 13 Reasons


Patti is Your Personal Training Expert Exercise
and Nutrition Programs for REAL PEOPLE




Lets face it, some days you just dont feel like exercising.

You get too busy, too stressed and quite simply too tired.

Heres a list of 13 of the top reasons to exercise. Pull out this list and read it when youre having one of those days.

1. To Prevent Disease
Exercise has been proven to reduce the risk of just about every single health problem known to man, from stroke to heart disease to cancer and osteoporosis. Exercise is also a great defense against type 2 diabetes, which is one of the most widely growing diseases of our time.

2. To Look Great
Exercise firms your body, improves posture and even makes your skin glow. Looking your best is a wonderful result of regular exercise.

3. To Lose Weight and Keep It Off
Exercise burns fat and prevents future fat storage. If you want to have a thinner, healthier body, exercise is the answer.

4. To Have More Energy
Anyone who exercises regularly will tell you that they are more energetic, less easily irritated and are more peaceful.

5. To Sleep Better
Exercise boosts energy levels, but also wears you out. It makes you feel more vibrant during the day and sleep better at night.

6. To Age Slower
Exercise is one of the most effective ways to fight aging. When you age your body loses muscle and bone, while the loss of both are drastically reduced with regular exercise. Exercise also helps reduce inflammation.

7. To Relieve Back Pain
In most cases, the best thing that you can do for back pain is to move and strengthen those muscles. Consult your physician or physical therapist for guidance.

8. To Ease Depression
Exercise has been proven to reduce depression – sometimes even as effectively as medication. Just chalk this up as yet another amazing benefit to exercise.

9. To Reduce Aches and Pains
By strengthening muscles around your damaged joints youre able to use exercise to reduce joint pain and overall aches. Always consult your physician before starting an exercise program, especially if you have chronic joint pain.

10. To Stay Mentally Sharp
Exercise has been shown to improve memory and other cognitive functions, and seems to have a protective effect against dementia. A Harvard University researcher called exercise "Miracle-Gro for the brain."

11. To Enjoy Your Lifestyle
Whatever it is that you love in life – your kids, travel, sports, fashion - it is all more enjoyable when experienced in a fit and healthy body. Exercise so that you are able to enjoy all the great things in life.

12. To Reduce Sick Days
People who exercise regularly are 50% less likely to call in sick to work. A regular exercise program reduces colds and upper respiratory infections.

13. To Boost Confidence
Being fit, feeling healthy and having energy are all building blocks to having great confidence. There is no better confidence booster than sticking with a regular exercise program.

Regular exercise gives you so many amazing benefits, as youve seen from the above list. Call or email me today to get started on the exercise program that will change your life forever.


PATTI GOEWEY,
Las Vegas Nevada,
Join Pattis News Letter here:
http://www.pattigoewey.com/

Exercise and Type 2 Diabetes

One of the most undemanding and the most workable ways to knock over blood sugar amount, eliminate the dangers of “cardiovascular disease,” and perk up health and welfare in general is exercise.

In spite of that, in today’s inactive world where almost every indispensable job can be carried out online, from the ergonomic chair in front of a computer, or with a streaming line of messages from a fax machine, exercising can be a hard argument to win over.

The Weight of Exercise

Everyone should exercise, yet the health experts tells us that only 30% of the United States population gets the recommended thirty minutes of daily physical activity, and 25% are not active at all. In fact, inactivity is thought to be one of the key reasons for the surge of type 2 diabetes in the U.S., because inactivity and obesity promote insulin resistance.

The good news is that it is never too late to get moving, and exercise is one of the easiest ways to start controlling your diabetes. For people with type 2 diabetes in particular, exercise can improve insulin sensitivity, lower the risk of heart disease, and promote weight loss.

Type 2 Diabetes

Diabetes is on the rise. The number of people diagnosed with diabetes every year increased by 48% between 1980 and 1994. Nearly all the new cases are Type 2 Diabetes, or adult-onset, the kind that moves in around middle age. Symptoms of Type 2 Diabetes include increased thirst, appetite, and need to urinate; feeling tired, edgy, or sick to the stomach; blurred vision; tingling or loss of feeling in the hands.

The causes of type 2 diabetes are complex and not completely understood, although research is uncovering new clues at a rapid pace.

However, it has already been proven that one of the reasons for the boom in type 2 diabetes is the widening of waistbands and the trend toward a more deskbound and inactive lifestyle in the United States and other developed countries. In America, the shift has been striking; in the 1990s alone, obesity increased by 61% and diagnosed diabetes by 49%.

For this reason, health experts encourage those who already have type 2 diabetes to start employing the wonders that exercise can do for them. Without exercise, people have the tendency to become obese. Once they are obese, they have bigger chances of accumulating type 2 diabetes.

Today, the U.S. Department of Health and Human Services reports that over 80% of people with type 2 diabetes are clinically overweight. Therefore, it is high time that people, whether inflicted with type 2 diabetes or not, should start doing those jumping and stretching activities.

Getting Started

The first order of business with any exercise plan, especially if you are a “dyed-in-the-wool” sluggish, is to consult with your health care provider. If you have cardiac risk factors, the health care provider may want to perform a stress test to establish a safe level of exercise for you.

Certain diabetic complications will also dictate what type of exercise program you can take on. Activities like weightlifting, jogging, or high-impact aerobics can possibly pose a risk for people with diabetic retinopathy due to the risk for further blood vessel damage and possible retinal detachment.

If you are already active in sports or work out regularly, it will still benefit you to discuss your regular routine with your doctor. If you are taking insulin, you may need to take special precautions to prevent hypoglycemia during your workout.

Start Slow

For those who have type 2 diabetes, your exercise routine can be as simple as a brisk nightly neighborhood walk. If you have not been very active before now, start slowly and work your way up. Walk the dog or get out in the yard and rake. Take the stairs instead of the elevator. Park in the back of the lot and walk. Every little bit does work, in fact, it really helps a lot.

As little as 15 to 30 minutes of daily, heart-pumping exercise can make a big difference in your blood glucose control and your risk of developing diabetic complications. One of the easiest and least expensive ways of getting moving is to start a walking program. All you need is a good pair of well-fitting, supportive shoes and a direction to head in.

Indeed, you do not have to waste too many expenses on costly “health club memberships,” or the most up-to-date health device to start pumping those fats out. What you need is the willingness and the determination to start exercising to a healthier, type 2 diabetes-free life.

The results would be the sweetest rewards from the effort that you have exerted.